Rabbit Polyclonal Antibody to IRF6

包装: 1G|100G|500G|1KG|100KG

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别名:LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Specification
Aliases	LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
Swissprot	O14896
WB Predicted band size	53 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human IRF6
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/50-1/200
ELISA	1/1000-1/2000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 231 cells, mouse kidney tissue, Mouse lung tissue, Primary antibody: P07391(IRF6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07391(IRF6 Antibody) at dilution 1/50. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07391(IRF6 Antibody) at dilution 1/50. (Original magnification: ×200)